Best Vitamin K1 (Phylloquinone) Supplements in the USA - Top 6 for 2026
Published on Wednesday, February 25, 2026
Vitamin K1, also known as phylloquinone, is a fat-soluble vitamin essential for several bodily functions. One of its most critical roles is supporting normal blood clotting, which helps prevent excessive bleeding. It also contributes to bone health by enabling the carboxylation of osteocalcin, a protein that helps bind calcium into bone tissue, improving calcium utilization and supporting overall skeletal strength. In the USA, Vitamin K1 appeals to a broad range of consumers: health-conscious adults seeking targeted bone and cardiovascular support, people looking to complement a diet low in leafy greens, and those prioritizing simple, single-nutrient supplements. Market trends through 2026 show steady growth driven by increased public awareness of bone health, preventive care, and the demand for clean-label products. American shoppers often favor recognizable brands, transparent ingredient sourcing, third-party testing, non-GMO and allergen-friendly formulations, clear dosing, and cost-effective options. Practical factors such as tablet size, vegetarian or vegan formulations, and clear guidance on interactions with medications also shape buying decisions. Because Vitamin K1 is fat soluble, consumers often choose formulations that emphasize bioavailability or advise taking the supplement with a meal containing healthy fats.
Top Picks Summary
Solgar Vitamin K1 100 mcg Tablets
Solgar's Vitamin K1 100 mcg tablets are positioned as a premium, well-documented option for phylloquinone thanks to the brand's long track record for high-quality manufacturing and clean excipients. Compared with budget brands on this list, Solgar delivers greater formulation transparency and perceived stability, which can justify the higher per-tablet cost for consumers prioritizing manufacturing pedigree over lowest price.
NOW Foods Vitamin K-1 100 mcg Phylloquinone
NOW Foods' Vitamin K-1 100 mcg Phylloquinone is a market leader for value, combining broad availability, competitive pricing, and a reputation for routine testing. It undercuts many premium competitors like Solgar and Life Extension on price while maintaining solid quality, making it a practical everyday Vitamin K1 choice for cost-conscious shoppers who still want reliable third-party assurance.
Carlson Labs Vitamin K1 100 mcg
Carlson Labs' Vitamin K1 100 mcg is known for its emphasis on purity and rigorous quality control, often favored by consumers seeking clinical-grade supplementation for phylloquinone. Technically it leans toward stable, bioavailable formulations and sits in the mid-price tier—more costly than discount labels but typically more affordable than high-potency specialists—offering a balance of lab-tested reliability and reasonable cost.
Life Extension Vitamin K1 1000 mcg
Life Extension's Vitamin K1 1000 mcg stands out as the high-potency option for phylloquinone, aimed at users or clinicians needing therapeutic dosing beyond standard 100 mcg products. Its technical advantage is the significantly higher dosage and alignment with research-backed, specialty formulations, though this clinical focus comes with a premium price compared with the standard-dose offerings from Solgar, NOW, and others.
Puritan's Pride Vitamin K1 100 mcg
Puritan's Pride offers a straightforward, budget-friendly Vitamin K1 100 mcg that competes primarily on price, making it attractive for consumers seeking basic phylloquinone supplementation without frills. While it lacks some of the extra testing transparency or specialty formulations of brands like Carlson or Life Extension, it undercuts many competitors and is a practical choice for routine, cost-sensitive use.
Solaray Vitamin K1 Phylloquinone 100 mcg
Solaray's Vitamin K1 Phylloquinone 100 mcg blends retail accessibility with formulation variety, often providing vegetarian or specialty capsule options that appeal to niche preferences. Financially it sits between discount and premium labels, offering competitive pricing with more formulation choices than some mass-market brands, though it is not positioned as a high-potency clinical product like the Life Extension option.
What the Research Says About Vitamin K1
Scientific research supports Vitamin K1's role in blood clotting and its contribution to bone health through activation of vitamin K-dependent proteins. Clinical trials and observational studies have demonstrated that adequate Vitamin K intake helps maintain proper coagulation and supports markers of bone metabolism. Evidence is stronger for the biochemical effects, such as improved carboxylation of osteocalcin, while long-term outcomes like fracture reduction are more variable and sometimes stronger for Vitamin K2 forms in specific studies. Overall, Vitamin K1 is considered safe at typical supplemental doses and may be a useful addition for people with low dietary intake of leafy greens or those advised by a healthcare provider to increase intake.
Blood clotting: Vitamin K1 is required for the liver to produce several clotting factors. Without enough K1, clotting is impaired.
Bone health: Research shows Vitamin K1 supports carboxylation of osteocalcin, which helps bone mineralization and may support bone density over time.
Cardiovascular effects: Some studies suggest vitamin K status relates to vascular calcification risk, though evidence is mixed and often stronger for Vitamin K2 variants.
Safety and interactions: Vitamin K1 is generally safe at recommended doses. It can interact with anticoagulant medications such as warfarin, so individuals on these drugs should consult their healthcare provider before supplementing.
Absorption tips: Because K1 is fat soluble, taking it with a meal that contains dietary fat improves absorption, which is why many formulations include dosing guidance to take with food.
Frequently Asked Questions
Which Vitamin K1 100 mcg supplement should I buy?
If you want a dependable everyday choice, pick Solgar Vitamin K1 100 mcg Tablets—each tablet provides 100 mcg phylloquinone, has a 4.7 average rating, and is described as well-documented with quality manufacturing and product testing.
Does NOW Foods Vitamin K-1 100 mcg include the dose?
Yes—NOW Foods Vitamin K-1 100 mcg Phylloquinone provides 100 mcg of Vitamin K1 (phylloquinone) per tablet, with a 4.6 average rating, and is noted as manufactured in GMP-compliant facilities.
How does Carlson Labs Vitamin K1 100 mcg value compare?
The provided info doesn’t list a price for Carlson Labs Vitamin K1 100 mcg, but it does say it sits in the mid-price tier, provides 100 mcg phylloquinone per serving, and has a 4.5 average rating with emphasis on purity and independent testing.
Is Solgar Vitamin K1 100 mcg good for daily use?
Solgar Vitamin K1 100 mcg Tablets are presented as convenient daily supplementation—each tablet delivers 100 mcg phylloquinone (Vitamin K1) and averages a 4.7 rating; the provided data doesn’t specify warranty duration.
Conclusion
If you are exploring Vitamin K1 supplements in the USA for 2026, the top options listed here — Solgar Vitamin K1 100 mcg Tablets, NOW Foods Vitamin K-1 100 mcg Phylloquinone, Carlson Labs Vitamin K1 100 mcg, Life Extension Vitamin K1 1000 mcg, Puritan's Pride Vitamin K1 100 mcg, and Solaray Vitamin K1 Phylloquinone 100 mcg — cover a range of doses and brand strengths. For most users seeking a reliable daily maintenance supplement, Solgar Vitamin K1 100 mcg Tablets stands out as the best overall choice because of its consistent quality, straightforward dosing, and strong brand reputation. If you have specific needs, such as higher-dose therapy or budget-friendly alternatives, the other products on this page may be more appropriate. I hope you found what you were looking for; you can refine or expand your search using the search bar to compare price, form, third-party testing, or user reviews.